Hi Brandon,
I am thinking you are referring to modify VBOs which are used by Business Process already in production.
Theoretically, if the VBOs getting modified are the fundamental element (not calling other VBOs), as long as the Input parameters and Output parameters are correct and compliant to the original one, and the modified codes got all the required variables and parameters defined correctly locally, it is unlikely you will see problem from the calling process.
Hope I answered your question.
Henry