As with the installation of any new version of Blue Prism (either a move from 32 to 64 bit, or an upgrade to a new version of the product), my advice would be the same. Create a Sandbox installation environment (new database/environment) and regression test everything you have previously built.
I would expect the difference to be either non-existent or very minimal, with a slim chance that for some of your applications you may need to amend the Application Modeller mode (32/64/internal/external) for your interfaces to continue working.