Blue Prism should run in a virtualized infastructure, not on a local physical desktop, so there will be no monitor/mouse/keyboard. The expectation is that developers who have completed the Blue Prism training can create solutions that run lights off in that virtualized environment.
Our training path for technical leads/architects is very clear on the platform architecture so maybe reach out to someone either within your own organisation or at one of our Partner organsation to have an in-depth discussion on how the Blue Prism platform solution works.